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Identification of Gallagyldilacton as a Mutation-Biased EGFR Inhibitor from Punica granatum Peel via Integrative Computational Analysis

2026-03-10

Abstract excerpt

<title>Abstract</title> <p> Non-small cell lung cancer (NSCLC) accounts for the majority of lung cancer cases worldwide and remains a leading cause of cancer-related mortality. Aberrant activation of the epidermal growth factor receptor (EGFR), driven by overexpression or mutation, represents a central oncogenic mechanism in NSCLC and a primary target of tyrosine kinase inhibitors (TKIs). Despite substantial cli...

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Literature Corpus work
78352153-b2b4-5c68-b485-dcfddb5be67c
DOI
10.21203/rs.3.rs-8583101/v1
Open publication

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Identification of Gallagyldilacton as a Mutation-Biased EGFR Inhibitor from Punica granatum Peel via Integrative Computational AnalysisDOI 10.21203/rs.3.rs-8583101/v1
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