Article
Identification of crucial genes and biological pathways in lung adenocarcinoma by network pharmacology, molecular docking, and simulation studies
2026-03-26
Abstract excerpt
<title>Abstract</title> <p>Lung adenocarcinoma (LUAD) remains a leading cause of cancer-related mortality, largely due to chemoresistance treatment-associated toxicity. This research employed integrated network pharmacology, molecular docking, and molecular dynamics (MD) simulation to investigate the therapeutic potential of bioactive compounds from Pleurotus membranaceus (PM). Four of the 23 bioactive compounds...
Topics
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- Berberine and alkaloids research
- Bone and Dental Protein Studies
- Cholinesterase and Neurodegenerative Diseases
- Computational Drug Discovery Methods
- Digestive system and related health
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Lung Cancer Treatments and Mutations
- Microbial Natural Products and Biosynthesis
Identifiers and source
- Literature Corpus work
- 11a95488-1e30-55b0-9e16-c9d10b325e62
- DOI
- 10.21203/rs.3.rs-9147467/v1
