Article

In Silico Screening and Structural Optimization of Curcumin Derivatives with Potential Anticancer Activity

2025-09-08

Abstract excerpt

<title>Abstract</title> <p>Lung cancer remains the leading cause of cancer-related deaths globally, responsible for 18.4% of the 9.6 million cancer deaths reported in 2018. Non-small cell lung cancer (NSCLC) accounts for approximately 85% of cases, with epidermal growth factor receptor (EGFR) mutations representing key therapeutic targets. Although EGFR tyrosine kinase inhibitors (TKIs) such as gefitinib, erlotin...

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Literature Corpus work: 163df2f8-e67c-5679-bb3e-4c8141b26b0b
DOI: 10.21203/rs.3.rs-7082373/v1

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