Back to search

Article

Network Pharmacology-guided Identification and Molecular Validation of Multi-Target Phytoconstituents from Gmelina arborea against Alzheimer’s Disease

2026-01-30

Abstract excerpt

<title>Abstract</title> <p> Alzheimer’s disease (AD), one of the most prevalent neurodegenerative disorders, remains without a definitive cure due to its complex multifactorial pathogenesis. Conventional drug development strategies, targeting single pathway, have demonstrated limited success, necessitating a paradigm shift towards multi-target therapeutics. In this study, we systematically investigated the thera...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
a8d3d7a0-9473-5f4c-a2b4-318a28ea2cb5
DOI
10.21203/rs.3.rs-7399280/v2
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Network Pharmacology-guided Identification and Molecular Validation of Multi-Target Phytoconstituents from Gmelina arborea against Alzheimer’s DiseaseDOI 10.21203/rs.3.rs-7399280/v2
Network Pharmacology-guided Identification and Molecular Validation of Multi-Target Phytoconstituents from Gmelina arborea against Alzheimer’s DiseaseSemantic proximity
Network pharmacology and pharmacokinetics strategy decoded the molecular basis of Phyto-neurotherapeutic potential of Zingiber officinaleSemantic proximity
Polyphenols in the Pipeline: Network-Based Docking, Molecular Dynamics and ADMET Studies of Flavonoids against Alzheimer’s diseaseSemantic proximity
The Network Pharmacology Study And Molecular Docking To Investigate The Potential Mechanism of Acoritataninowii Rhizoma Against Alzheimer's DiseaseSemantic proximity
Network Pharmacology Unveils Potential Targets of Madhuca longifolia in Treating Alzheimer’s Disease: An Advanced Strategy in Drug DiscoverySemantic proximity
Network Pharmacology and molecular docking approach to unveil the mechanism of <i>Hypericum perforatum</i> in the management of Alzheimer’s disorderSemantic proximity
Exploration of the treatment mechanism of Rehmanniae Radix Praeparata for Parkinson's disease, based on network pharmacology, molecular docking, and experimental validationSemantic proximity
Xanthoangelol Mitigates Neuroinflammation and Hypoxia via MAPK and HIF-1 Signaling Modulation: Network Pharmacology and In-Vivo Approach in a Haloperidol-Induced Model of Parkinson’s DiseaseSemantic proximity
Targeting PD-1/PD-L1-MAPK1 Signaling by a Novel Synergistic Combination of Rivastigmine and Epigallocatechin in Alzheimer’s Disease: An Integrated Insilico ApproachSemantic proximity
Exploring the potential mechanism of Polygonatum sibiricum for Alzheimer's disease based on network pharmacology and molecular dockingSemantic proximity
Network pharmacology and bioinformatics approach reveals the therapeutic mechanism of action of curcumin in Alzheimer diseaseSemantic proximity
An Integrated Pharmacoinformatics analysis on Prosopis juliflora bioactives to divulge EGFR-Mediated Crosstalk in the Gut–Brain AxisSemantic proximity
Select a neighboring publication to make it the new centre.