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Article

Enhanced Anti-Tumor Effects by Combination of Tucatinib and Radiation in HER2-Overexpressing Human Cancer Cell Lines

2024-04-09

Abstract excerpt

<title>Abstract</title> <p>Background Tucatinib (TUC), a HER2-directed tyrosine kinase inhibitor, is the first targeted drug demonstrating intracranial efficacy and significantly prolonged survival in metastatic HER2-positive breast cancer (BC) patients with brain metastases. Current treatments for brain metastases often include radiotherapy, but little is known about the effects of combination treatment with TU...

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Literature Corpus work
7832b453-4bcf-5b40-b154-b1e28f0020f6
DOI
10.21203/rs.3.rs-4210466/v1
Open publication

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Enhanced Anti-Tumor Effects by Combination of Tucatinib and Radiation in HER2-Overexpressing Human Cancer Cell LinesDOI 10.21203/rs.3.rs-4210466/v1
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