Article
Association analysis between the tag single nucleotide polymorphisms of DENND1A and the risk of polycystic ovary syndrome in Chinese Han women.
BMC medical genetics - 15 Jan 2020
Zhu Ya-Nan, Zhang Yi-Ting, Liu Qin, Shen Shan-Mei, Zou Xiang, Cao Yun-Xia, Wang Wen-Jun, Yi Long, Gao Qian, Yang Wei-Dong, Wang Yong
Abstract excerpt
BACKGROUND: The DENND1A gene is one of the most important sites associated with polycystic ovary syndrome (PCOS). We attempted to analyze the correlation between five single nucleotide polymorphisms (SNPs) in the DENND1A gene and the development of PCOS. METHODS: A total of 346 PCOS patients and 225 normal ovulatory women were involved in the case-control study. Clinical variables and hormones were recorded....
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