Article

SARS-CoV2 drives JAK1/2-dependent local and systemic complement hyper-activation

2020-06-09

Abstract excerpt

<title>Abstract</title> <p>Patients with coronavirus disease 2019 (COVID-19) present with a range of devastating acute clinical manifestations affecting the lungs, liver, kidneys and gut. The best-characterized entry receptor for the disease-causing virus SARS-CoV2, angiotensin converting enzyme (ACE) 2, is highly expressed in these tissues. However, the pathways that underlie the disease are still poorly underst...

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Literature Corpus work: 779fe61f-e054-50b2-85f2-2578dd33de7b
DOI: 10.21203/rs.3.rs-33390/v1

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