Article

PARP inhibitor and immune checkpoint inhibitor may have synergism efficacy in gallbladder cancer

2023-09-07

Abstract excerpt

<title>Abstract</title> <p>Background Gallbladder cancer (GBC) is aggressive with poor prognosis. PARP inhibitors (PARPi) targets PARP enzymes, showing efficacy in BRCA-mutated patients. Immunotherapy, especially immune checkpoint inhibitors (ICIs), has transformed cancer treatment. Yet, the combined impact of PARPi and ICIs in GBC is unclear. Methods We presented a groundbreaking case of a GBC patient with BRC...

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Literature Corpus work: 778aedea-dbd3-5481-b797-2c5514b04564
DOI: 10.21203/rs.3.rs-3313018/v1

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