Back to search

Article

Poor prognosis of stage I lung adenocarcinoma patients determined by elevated expression over pre/minimally invasive status of COL11A1 and THBS2 in the focal adhesion pathway

2022-01-13

Abstract excerpt

<title>Abstract</title> <p>Patients with adenocarcinomas in situ (AIS) and minimally invasive (MIA) lung adenocarcinoma (LUAD) are curable by surgery, whereas 20% stage I patients die within five years post-operative. We hypothesize that poor-prognosis stage I patients may exhibit key molecular characteristics deviating from AIS/MIA. Focal adhesion (FA) was identified as the only pathway significantly perturbed a...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
7735fd96-0514-5b9b-8f89-adcad1596e0f
DOI
10.21203/rs.3.rs-1218087/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Poor prognosis of stage I lung adenocarcinoma patients determined by elevated expression over pre/minimally invasive status of COL11A1 and THBS2 in the focal adhesion pathwayDOI 10.21203/rs.3.rs-1218087/v1
Poor prognosis of stage I lung adenocarcinoma patients determined by elevated expression over pre/minimally invasive status of COL11A1 and THBS2 in the focal adhesion pathwaySemantic proximity
Analysis of cancer-associated fibroblasts related genes identifies COL11A1 associated with lung adenocarcinoma prognosisSemantic proximity
Unraveling the Complexity: Expression Patterns and Prognostic Value of Cell Adhesion Junction Regulatory Genes in Hepatocellular CarcinomaSemantic proximity
Myofibroblasts Derived Type V Collagen Promoting Tissue Mechanical Stress and Facilitating Metastasis and Therapy Resistance of Lung Adenocarcinoma CellsSemantic proximity
Predictive value of focal adhesion-related genes for prognosis and response to immunotherapy in glioma patientsSemantic proximity
Differentially Expressed Genes Regulating the Progression of Ductal Carcinoma <i>In Situ</i> to Invasive Breast CancerSemantic proximity
Integrative Network Analysis of Early-Stage Lung Adenocarcinoma Identifies Aurora Kinase Inhibition as Interceptor of Invasion and ProgressionSemantic proximity
Cell adhesion and polarity in squamous cell carcinoma of the lung.Semantic proximity
Biomarker Discovery in Non–Small Cell Lung Cancer: Integrating Gene Expression Profiling, Meta-analysis, and Tissue Microarray ValidationSemantic proximity
A Potential Role of Collagens Expression in Distinguishing Between Premalignant and Malignant Lesions in StomachSemantic proximity
Cancer‐associated fibroblast migration in non‐small cell lung cancers is modulated by increased integrin α11 expressionSemantic proximity
Matrix Metallopeptidase-Gene Signature Predicts Stage I Lung Adenocarcinoma Survival Outcomes.Semantic proximity
Select a neighboring publication to make it the new centre.