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Cancer‐associated fibroblast migration in non‐small cell lung cancers is modulated by increased integrin α11 expression

8 Mar 2021

Abstract excerpt

Cancer-associated fibroblasts (CAFs) regulate cancer progression through the modulation of extracellular matrix (ECM) and cancer cell adhesion. While undergoing a series of phenotypic changes, CAFs control cancer-stroma interactions through integrin receptor signaling. Here, we isolated CAFs from patients with non-small-cell lung cancer (NSCLC) and examined their gene expression profiles. We identified collagen...

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PMID: 33682233
DOI: 10.1002/1878-0261.12937

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