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Differentially Expressed Genes Regulating the Progression of Ductal Carcinoma <i>In Situ</i> to Invasive Breast Cancer

3 Jul 2012

Abstract excerpt

Molecular mechanisms mediating the progression of ductal carcinoma in situ (DCIS) to invasive breast cancer remain largely unknown. We used gene expression profiling of human DCIS (n = 53) and invasive breast cancer (n = 51) to discover uniquely expressed genes that may also regulate progression. There were 470 total differentially expressed genes (≥2-fold; P < 0.05). Elevated expression of genes involved in...

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PMID: 22751464
DOI: 10.1158/0008-5472.can-12-0636

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