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Article

Branched-Chain Amino Acid Metabolism is Regulated by ERRα in Primary Human Myotubes and is Further Impaired by Glucose Loading in Type 2 Diabetes

2020-07-25

Abstract excerpt

<h4>Aims/hypothesis</h4> Increased levels of branched-chain amino acids (BCAAs) are associated with type 2 diabetes pathogenesis. However, most metabolomic studies are limited to an analysis of plasma metabolites under fasting conditions, rather than the dynamic shift in response to a metabolic challenge. Moreover, metabolomic profiles of peripheral tissues involved in glucose homeostasis are scarce and the trans...

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Literature Corpus work
772ff944-e194-527b-8201-85c07ec72c63
DOI
10.1101/2020.07.24.218099
Open publication

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Branched-Chain Amino Acid Metabolism is Regulated by ERRα in Primary Human Myotubes and is Further Impaired by Glucose Loading in Type 2 DiabetesDOI 10.1101/2020.07.24.218099
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