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Article

Metabolome genome-wide association analyses identify a splice mutation in AADAT affects lysine degradation in duck skeletal muscle.

Science China. Life sciences - 1 Jul 2025

Liu Dapeng, Fan Wenlei, Yang Youyou, Guo Zhanbao, Xu Yaxi, Hu Jian, Liu Tong, Yu Simeng, Zhang He, Tang Jing, Hou Shuisheng, Zhou Zhengkui

Abstract excerpt

Metabolites in skeletal muscles play an important role in their growth, development, immunity and other physiological activities. However, the genetic basis of metabolites in skeletal muscle remains poorly understood. Here, we identified 247 candidate divergent regions containing 905 protein-coding genes closely related to metabolic pathways, including lysine degradation and fatty acid biosynthesis. We then...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40208415
DOI: 10.1007/s11427-024-2882-x

Genes

AADAT
CR1
F2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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