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Efficient expression in the prokaryotic host system, purification and structural analyses of the recombinant human ACE2 catalytic subunit as a hybrid protein with the B subunit of cholera toxin (CTB-ACE2)

2023-07-03

Abstract excerpt

<title>Abstract</title> <p>Angiotensin-converting enzyme 2 (ACE2) has a specific interaction with the coronavirus spike protein, enabling its entry into human cells. This membrane enzyme converts angiotensin II into angiotensin 1–7, which has an essential role in protecting the heart and improving lung function. Many therapeutic properties have been attributed to the human recombinant ACE2 (hrACE2), especially in...

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Literature Corpus work
76bf98fe-4457-500a-b813-93e00310d456
DOI
10.21203/rs.3.rs-3121889/v1
Open publication

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Efficient expression in the prokaryotic host system, purification and structural analyses of the recombinant human ACE2 catalytic subunit as a hybrid protein with the B subunit of cholera toxin (CTB-ACE2)DOI 10.21203/rs.3.rs-3121889/v1
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