Article

Parkinson’s disease is associated with an imbalance in circular RNA expression

2023-08-05

Abstract excerpt

<title>Abstract</title><p>Neurodegeneration in Parkinson’s disease (PD) precedes diagnosis by years. Early neurodegeneration may be reflected in RNA levels and measurable as a biomarker. Here, we present the largest quantification of whole blood linear and circular RNAs (circRNA) in early-stage PD, using RNA sequencing data from two cohorts (PPMI = 259 PD, 161 Controls; ICICLE-PD = 48 PD, 48 Controls). We identifi...

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Literature Corpus work: 6bd4bdde-2b59-5c1f-83b5-4f96156de93f
DOI: 10.21203/rs.3.rs-3202518/v1

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