Article

Mesenchymal stem cells accelerated growth and metastasis of neuroblastoma and preferentially homed towards both primary and metastatic loci in orthotopic neuroblastoma model

2020-10-21

Abstract excerpt

<h4>Background: </h4> Majority of neuroblastoma patients develop metastatic disease at diagnosis and their prognosis is poor with current therapeutic approach. Major challenges are how to tackle the mechanisms responsible for tumorigenesis and metastasis. Human mesenchymal stem cells (hMSCs) may be actively involved in the constitution of cancer microenvironment. <h4>Methods: </h4>: In our study, an orthotopic neu...

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Literature Corpus work: 7693f0c8-a68b-55bb-86a8-d34e986eed44
DOI: 10.21203/rs.3.rs-21935/v2

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