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Article

Neuroblastoma models for insights into tumorigenesis and new therapies.

Expert opinion on drug discovery - 1 Jan 2015

Kiyonari Shinichi, Kadomatsu Kenji

Abstract excerpt

INTRODUCTION: Neuroblastoma is the most common extracranial solid tumor in children. It occurs in the adrenosympathetic lineage, which is derived from the neural crest. MYCN amplification is found in about 20% of cases and is the most powerful prognostic factor. Anaplastic lymphoma kinase (ALK) m...

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Source

Identifiers

PMID: 25345447
DOI: 10.1517/17460441.2015.974544

Genes

MYCN
ALK
DBH

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25345447-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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