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Cancer Stem Cells and Their Interaction with the Tumor Microenvironment in Neuroblastoma

31 Dec 2015

Abstract excerpt

Neuroblastoma, a solid tumor arising from neural crest cells, accounts for over 15% of all pediatric cancer deaths. The interaction of neuroblastoma cancer-initiating cells with their microenvironment likely plays an integral role in the maintenance of resistant disease and tumor relapse. In this review, we discuss the interaction between neuroblastoma cancer-initiating cells and the elements of the tumor...

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PMID: 26729169
DOI: 10.3390/cancers8010005

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