Epigenetic signature of human immune aging: the GESTALT study

Abstract excerpt

<h4>ABSTRACT</h4> Age-associated DNA methylation in blood cells convey information on health status. However, the mechanisms that drive these changes in circulating cells and their relationships to gene regulation are unknown. We identified age-associated DNA methylation sites in six purified blood borne immune cell types (naïve B, naïve CD4 + and CD8 + T cells, granulocytes, monocytes and NK cells) collected f...

Topics

Open a Topic to create a Post that cites this publication.

• Gene Regulatory Networks
• Aging
• DNA
• Epigenetics and DNA Methylation
• Follow-Up Studies
• Gene Expression
• Gene Expression Profiling
• Transcriptome

Identifiers and source

Literature Corpus work

768226f8-1890-56b8-b5f6-aa48c308f252

DOI

10.1101/2023.01.23.525162