Article

Targeting the Id1-Kif11-Aurka axis in triple negative breast cancer using combination therapy

2019-09-11

Abstract excerpt

Evidence points to breast cancer following a hierarchical model, with Cancer Stem Cells (CSCs) driving critical phenotypes of the bulk tumor. Chemoresistant CSCs are not an abstract concept but have clinical consequences as they drive relapse and ultimately lead to mortality in patients, making it imperative to understand how these subpopulations of cells survive. Our previous work (1-2) has demonstrated that the...

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Literature Corpus work: 7653a482-2f1b-5fbb-93a7-8094d4240cfa
DOI: 10.1101/760686

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