Article

ALTERATIONS IN PEROXISOMAL-MITOCHONDRIAL INTERPLAY IN SKELETAL MUSCLE ACCELERATES MUSCLE DYSFUNCTION

2024-04-28

Abstract excerpt

<h4>ABSTRACT</h4> Whole-body energy expenditure, as well as glucose and lipid metabolism, are regulated by skeletal muscles, which account for 40-50% of human body mass. Peroxisomes are dynamic organelles that play a crucial role in lipid metabolism and clearance of reactive oxygen species, however their role in muscles remains poorly understood. To clarify this issue, we generated a muscle-specific transgenic mo...

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Literature Corpus work: 763cc5a6-e701-5b5f-a988-fe0d9e601530
DOI: 10.1101/2024.04.25.591056

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