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Article

Peroxisomes are required for lipid metabolism and muscle function in Drosophila melanogaster.

PloS one - 1 Jan 2014

Faust Joseph E, Manisundaram Arvind, Ivanova Pavlina T, Milne Stephen B, Summerville James B, Brown H Alex, Wangler Michael, Stern Michael, McNew James A

Abstract excerpt

Peroxisomes are ubiquitous organelles that perform lipid and reactive oxygen species metabolism. Defects in peroxisome biogenesis cause peroxisome biogenesis disorders (PBDs). The most severe PBD, Zellweger syndrome, is characterized in part by neuronal dysfunction, craniofacial malformations, and low muscle tone (hypotonia). These devastating diseases lack effective therapies and the development of animal models...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24945818
DOI: 10.1371/journal.pone.0100213
PMCID: PMC4063865

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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