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Early age changes in mRNA expression related to NAD-dependent enzymes and mitochondrial proteins in the brain cortex of an Alzheimer’s disease mouse model

2022-03-28

Abstract excerpt

Oxidative stress and disturbances of mitochondria function in the brain have been recognized to play a crucial role in the pathophysiological mechanism of Alzheimer’s Disease (AD). However, little is known about these changes at an early age of AD, which could be crucial for therapeutic strategy for the disease. In this study, we used biochemical, and quantitative polymerase chain reaction for determination of exp...

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Literature Corpus work
76237b72-7c6c-58f4-b63c-ab38675033fc
DOI
10.21203/rs.3.rs-1481945/v1
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Early age changes in mRNA expression related to NAD-dependent enzymes and mitochondrial proteins in the brain cortex of an Alzheimer’s disease mouse modelDOI 10.21203/rs.3.rs-1481945/v1
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