Article
Early age changes in mRNA expression related to NAD-dependent enzymes and mitochondrial proteins in the brain cortex of an Alzheimer’s disease mouse model
2022-03-28
Abstract excerpt
Oxidative stress and disturbances of mitochondria function in the brain have been recognized to play a crucial role in the pathophysiological mechanism of Alzheimer’s Disease (AD). However, little is known about these changes at an early age of AD, which could be crucial for therapeutic strategy for the disease. In this study, we used biochemical, and quantitative polymerase chain reaction for determination of exp...
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Identifiers and source
- Literature Corpus work
- 76237b72-7c6c-58f4-b63c-ab38675033fc
- DOI
- 10.21203/rs.3.rs-1481945/v1
