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Relationship of cognition and Alzheimer’s disease with gastrointestinal tract disorders: a large-scale genetic overlap and Mendelian randomisation analysis

2022-10-27

Abstract excerpt

<title>Abstract</title> <p>Background Emerging observational evidence suggests links between cognitive impairment and a range of gastrointestinal tract (GIT) disorders; however, mechanisms underlying their relationships remain unclear. Leveraging several large-scale genome-wide association studies summary statistics, we comprehensively assessed genetic overlap and potential causality of cognitive traits and Alzh...

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Literature Corpus work
761e4776-814d-563c-9452-d4240fcbdd66
DOI
10.21203/rs.3.rs-2191133/v1
Open publication

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Relationship of cognition and Alzheimer’s disease with gastrointestinal tract disorders: a large-scale genetic overlap and Mendelian randomisation analysisDOI 10.21203/rs.3.rs-2191133/v1
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