Article

Common Mechanisms of Neuronal Dysfunction in Neurodegenerative Diseases: Insights and Therapeutic Strategies

2024-09-19

Abstract excerpt

Neurodegenerative diseases like Alzheimer's, Parkinson's, Amyotrophic Lateral Sclerosis, and Huntington's share common underlying mechanisms driving progressive neuronal dysfunction and death. Key pathological features include protein aggregation, oxidative stress, mitochondrial dysfunction, and neuroinflammation. In Parkinson's disease, disruption of cellular homeostasis results from alpha-synuclein aggregation,...

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Literature Corpus work: 75e46ddc-0a21-508e-be05-4f81d9782b83
DOI: 10.22541/au.172670595.54796055/v1

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