Article

Are Aspirin and Apixaban Sufficient to Prevent Immunothrombosis in COVID-19?

2020-12-29

Abstract excerpt

Severe COVID-19 disease is associated with respiratory and vascular injury and microvascular immunothrombosis mediated by complement activation, inflammatory lipid storm, platelet activation, platelet-leukocyte adhesion and activation of coagulation cascade. Amongst the inflammatory lipids, thromboxane A2 (TxA2) is a known key mediator of microvascular thrombosis. The levels of TxB2, a stable metabolite of TxA2 ar...

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Literature Corpus work: 0d62f17c-dcde-5968-85aa-71ea87c3db3a
DOI: 10.2139/ssrn.3755292

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