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SARS-CoV-2 promote autophagy to suppress type I interferon response

8 May 2021

Abstract excerpt

The outbreak of SARS-CoV-2 leads global epidemic with high morbidity and mortality. However, the pathophysiology of this deadly virus is complex and largely unknown. Autophagy is a highly conserved homeostatic process that allows cells to recycle their components. Several studies provided evidence that human coronavirus infections are closely related to various cellular aspects associated with autophagy. 1...

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PMID: 33966045
DOI: 10.1038/s41392-021-00574-8

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