Article

Site-1 Protease inhibits mitochondrial metabolism by controlling the TGF-β target gene MSS51

2022-08-24

Abstract excerpt

<h4>SUMMARY</h4> The mitochondrial response to changes in cellular energy demand is necessary for cellular adaptation and organ function. Many genes are essential in orchestrating this response, including the transforming growth factor (TGF)-β1 target gene MSS51, which is an inhibitor of skeletal muscle mitochondrial metabolism. Despite the potential importance of MSS51 in the pathophysiology of obesity and muscu...

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Literature Corpus work: 752958b4-899f-54e7-9aff-d4e32ef75cca
DOI: 10.1101/2022.08.24.504591

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