Viruses of Avian Origin for Cancer Virotherapy

Abstract excerpt

<title>Abstract</title> <p> Oncolytic viruses (OVs) can selectively infect and kill tumor cells. Although showing promise, several challenges impede OVs broad application in cancer therapy. A major obstacle is limited treatment duration due to preexisting or the induction of neutralizing immune responses toward the OVs following treatment. Widening the reservoir of OVs will allow replacement of treatment viruses...

Topics

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• Adenoviridae
• Animal Virus Infections Studies
• CAR-T cell therapy research
• Interferons
• Neoplasms
• Viral gastroenteritis research and epidemiology
• Viral Infectious Diseases and Gene Expression in Insects
• Virus-based gene therapy research

Identifiers and source

Literature Corpus work

75130e19-8875-56ce-a8d2-d471d3850a92

DOI

10.21203/rs.3.rs-6690670/v1