Article
Virus–Receptor Interactions and Virus Neutralization: Insights for Oncolytic Virus Development
1 Mar 2020
Abstract excerpt
Oncolytic viruses (OVs) are replication competent agents that selectively target cancer cells. After penetrating the tumor cell, viruses replicate and eventually trigger cell lysis, releasing the new viral progeny, which at their turn will attack and kill neighbouring cells. The ability of OVs to self-amplify within the tumor while sparing normal cells can provide several advantages including the capacity to...
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