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Extensive characterization of a Williams Syndrome murine model shows <i>Gtf2ird1</i> -mediated rescue of select sensorimotor tasks, but no effect on enhanced social behavior

2023-01-18

Abstract excerpt

Williams Syndrome is a rare neurodevelopmental disorder exhibiting cognitive and behavioral abnormalities, including increased social motivation, risk of anxiety and specific phobias along with perturbed motor function. Williams Syndrome is caused by a microdeletion of 26-28 genes on chromosome 7, including GTF2IRD1 , which encodes a transcription factor suggested to play a role in the behavioral profile of Willi...

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Literature Corpus work
74fe0ee1-6b74-5841-a0c9-0d05555e4c40
DOI
10.1101/2023.01.18.523029
Open publication

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Extensive characterization of a Williams Syndrome murine model shows <i>Gtf2ird1</i> -mediated rescue of select sensorimotor tasks, but no effect on enhanced social behaviorDOI 10.1101/2023.01.18.523029
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