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Article

Duplication of GTF2I results in separation anxiety in mice and humans.

American journal of human genetics - 8 Jun 2012

Mervis Carolyn B, Dida Joana, Lam Emily, Crawford-Zelli Nicole A, Young Edwin J, Henderson Danielle R, Onay Tuncer, Morris Colleen A, Woodruff-Borden Janet, Yeomans John, Osborne Lucy R

Abstract excerpt

Duplication (dup7q11.23) and deletion (Williams syndrome) of chromosomal region 7q11.23 cause neurodevelopmental disorders with contrasting anxiety phenotypes. We found that 30% of 4- to 12-year-olds with dup7q11.23 but fewer than 5% of children with WS or in the general population met diagnostic criteria for a separation-anxiety disorder. To address the role of one commonly duplicated or deleted gene in...

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Share to Chromosomes, Human, Pair 7

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Transcription Factors, TFII

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Source

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Identifiers

PMID: 22578324
DOI: 10.1016/j.ajhg.2012.04.012
PMCID: PMC3370270

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Duplication of GTF2I results in separation anxiety in mice and humans.PMID 22578324Read ↗

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