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A long-deletion mouse model of Williams syndrome reveals <i>Ncf1</i> -dependent modulation of vascular and neural phenotypes

2023-10-31

Abstract excerpt

Williams syndrome is a developmental disorder caused by a microdeletion entailing the loss of a single copy of 25-27 genes on chromosome 7q11.23. Patients suffer from cardiovascular and neuropsychological symptoms. Structural abnormalities of the cardiovascular system in Williams syndrome have been attributed to the hemizygous loss of the elastin ( ELN ) gene. In contrast, the neuropsychological consequences of W...

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Literature Corpus work
6cb9f7f6-be0b-54df-bb0d-e3050f331776
DOI
10.1101/2023.10.30.564727
Open publication

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A long-deletion mouse model of Williams syndrome reveals <i>Ncf1</i> -dependent modulation of vascular and neural phenotypesDOI 10.1101/2023.10.30.564727
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