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From Psychological Distress to Multi-System Morbidity: A Transdiagnostic Internalizing Factor Predicts Chronic Disease Onset

2026-05-25

Abstract excerpt

<title>Abstract</title> <p>Physical health and mental well-being are bidirectionally linked. While the impact of somatic health on mental well-being is extensively investigated, the reciprocal “mind-to-body” trajectory—how psychological distress contributes to multi-system physical disease—remains underexplored, particularly in general populations. Here, we systematically investigated the biological pathways link...

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Literature Corpus work
74ebde67-2719-507b-9bb6-a0dd1ddac583
DOI
10.21203/rs.3.rs-9436157/v1
Open publication

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