Article

Systems biology analysis of vasodynamics in mouse cerebral arterioles during resting state and functional hyperemia

2025-05-10

Abstract excerpt

Cerebral hemodynamics is tightly regulated by arteriolar vasodynamics. In this study, a systems biology approach was employed to investigate how the interplay between passive, myogenic, neurogenic, and astrocytic responses shapes arteriolar vasodynamics in small rodents. A model of neurovascular coupling is proposed in which neurons inhibit and dampen the myogenic response to promote vasodilation during activation...

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Identifiers and source

Literature Corpus work: 74db0e64-4cb5-5cd1-b0dc-40340a58e66a
DOI: 10.1101/2025.05.06.652356

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