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Identification of the CoA-ester intermediates and genes involved in the cleavage and degradation of the steroidal C-ring by <i>Comamonas testosteroni</i> TA441

2021-06-09

Abstract excerpt

<h4>ABSTRACT</h4> Comamonas testosteroni TA441 degrades steroids aerobically via aromatization of the A-ring accompanied by B-ring cleavage, followed by D- and C-ring cleavage. We previously revealed major enzymes and intermediate compounds in A,B-ring cleavage, β-oxidation cycle of the cleaved B-ring, and partial C,D-ring cleavage process. Here, we elucidated the C-ring cleavage and the β-oxidation cycle that fo...

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Literature Corpus work
7481558d-0420-5aa8-bd79-4889d29937ae
DOI
10.1101/2021.06.08.447645
Open publication

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