Article

Identification of “missing links” in C- and D-ring cleavage of steroids by <i>Comamonas testosteroni</i> TA441

2023-02-02

Abstract excerpt

<h4>ABSTRACT</h4> Comamonas testosteroni TA441 degrades steroids aerobically via aromatization and cleavage of the A- and B-ring, followed by D- and C-ring cleavage via b-oxidation. We previously characterized most of the above degradation steps; however, a few intermediate compounds remained unaccounted for. We hypothesized that cleavage of the D-ring at C13-17 required the ScdY hydratase and was followed by cle...

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Literature Corpus work: 21f39122-6c09-57ce-8eb0-395d60578184
DOI: 10.1101/2023.02.02.526765

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