Article

Single-cell transcriptomic construction of fibroblast score for analysis of immune infiltration in primary and metastatic ovarian cancer

2024-06-12

Abstract excerpt

<title>Abstract</title> <p>Purpose Ovarian cancer (OV) is a malignant gynecologic cancer with poor clinical outcomes and poor prognosis. The aim of this study was to explore the immune infiltration between primary and metastatic ovarian cancer and the function of fibroblast differential marker in ovarian cancer immunomodulation. Methods Obtained single-cell transcriptome datasets of primary ovarian cancer and m...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 8c238392-bd52-5a99-9907-f20788e3a3b0
DOI: 10.21203/rs.3.rs-4485189/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Single-cell transcriptomic construction of fibroblast score for analysis of immune infiltration in primary and metastatic ovarian cancerDOI 10.21203/rs.3.rs-4485189/v1Read

Identification of the immune subtype of ovarian cancer patients by integrated analyses of transcriptome and single-cell sequencing dataSemantic proximity Read

Identification of fibroblast subpopulations facilitating to chemotherapy resistance in metastasis of ovarian cancerSemantic proximity Read

Development a prognostic risk model based on B cell-related immune genes in Ovarian Cancer by integrative analysis of single-cell and bulk RNA sequencing dataSemantic proximity Read

Integration of scRNA-Seq and bulk RNA-Seq to Establish a Macrophage-related Prognostic Model in Ovarian CancerSemantic proximity Read

Single cell analysis of epithelial, immune, and stromal signatures and interactions in human ovarian cancerSemantic proximity Read

Single-Cell Transcriptomics Reveals Tissue Architecture in Ovarian CarcinosarcomaSemantic proximity Read

Single-cell analysis revealed that IL4I1 promoted ovarian cancer progressionSemantic proximity Read

Single-cell transcriptome analysis of epithelial, immune, and stromal signatures and interactions in human ovarian cancerSemantic proximity Read

Identification of a Gene Signature of Cancer-Associated Fibroblasts to Predict Prognosis in Ovarian CancerSemantic proximity Read

Integrated analysis of single-cell and bulk transcriptomic data reveals altered cellular composition and predictive cell types in endometriosisSemantic proximity Read

T cell-Macrophage Interactions Potentially Influence Chemotherapeutic Response in Ovarian Cancer PatientsSemantic proximity Read

Elucidating the tumor microenvironment interactions in breast, cervical, and ovarian cancer through single-cell RNA sequencingSemantic proximity Read