Article

IFN-γ Enhances the Efficacy of Exosomes Derived from Mesenchymal Stem Cells in Myocardial Infarction Rats via miR-21 Stimulated by STAT1

2021-11-10

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Mesenchymal stem cells (MSCs) activated with IFN-γ elicit more powerful physical effects. Exosomes (Exos) secreted from MSCs have protective against myocardial injury. The aim of this study was to investigate whether Exsos derived from IFN-γ-pretreated MSCs exhibit more potent cardioprotective function and the underlying mechanisms. <bold>Methods:</bold> Exos we...

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Literature Corpus work: b1d75e4c-189d-5d4b-8f37-de582c2cd1c2
DOI: 10.21203/rs.3.rs-1044001/v1

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