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Article

The ABC of Ribosome-Related Antibiotic Resistance

4 May 2016

Abstract excerpt

The increase in multidrug-resistant pathogenic bacteria is limiting the utility of our current arsenal of antimicrobial agents. Mechanistically understanding how bacteria obtain antibiotic resistance is a critical first step to the development of improved inhibitors. One common mechanism for bacteria to obtain antibiotic resistance is by employing ATP-binding cassette (ABC) transporters to actively pump the drug...

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Identifiers

PMID: 27143393
DOI: 10.1128/mbio.00598-16

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