Article

Exploring the role of glycans in the interaction of SARS-CoV-2 RBD and human receptor ACE2

2021-03-31

Abstract excerpt

COVID-19 is a highly infectious respiratory disease caused by the novel coronavirus SARS-CoV-2. It has become a global pandemic and its frequent mutations may pose new challenges for vaccine design. During viral infection, the Spike RBD of SARS-CoV-2 binds the human host cell receptor ACE2, enabling the virus to enter the host cell. Both the Spike and ACE2 are densely glycosylated, and it is unclear how distinctiv...

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Literature Corpus work: 742b3a08-66ae-5253-8be6-89608bc3c420
DOI: 10.1101/2021.03.30.437783

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