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Differential Interactions between Human ACE2 and Spike RBD of SARS-CoV-2 Variants of Concern

3 Dec 2021

Abstract excerpt

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of the current coronavirus disease 2019 (COVID-19) pandemic. It is known that the receptor-binding domain (RBD) of the spike protein of SARS-CoV-2 interacts with the human angiotensin-converting enzyme 2 (ACE2) receptor, initiating the entry of SARS-CoV-2. Since its emergence, a number of SARS-CoV-2 variants have been reported,...

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PMID: 34856802
DOI: 10.1021/acs.jctc.1c00965

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