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The Energy-Deficit Hypothesis of Autism: Multi-Cytokine Convergence on Mitochondrial Dysfunction: A Cerebral Energy-Deficit Hypothesis of Autism Spectrum Disorder

2026-08-13

Abstract excerpt

<h4>Background: </h4> Autism spectrum disorder (ASD) affects approximately 1-2% of children worldwide, yet its etiology remains incompletely understood. Emerging evidence suggests that offspring of parents with autoimmune diseases show elevated autism prevalence. Notably, children of parents or mothers with immune-related conditions, including psoriasis (OR 1.59), maternal type 1 diabetes (HR 2.36 in one large coh...

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Literature Corpus work: 741c534b-54d6-501c-80dc-92f42eae673b
DOI: 10.20944/preprints202512.2808.v12

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