Lead Induced, VDR Taq and MAO-A Associated Energy Metabolism Reduction, and CD4+CD3+ Lymphocytes-Dependent Inflammation as Main Pathogenetic Events in Autism Spectrum Disorders

Abstract excerpt

<title>Abstract</title> <p>Background Autism Spectrum Disorder (ASD) is characterized by persistent deficits in social communication and interaction and restricted-repetitive patterns of behavior, interests, or activities. ASD is generally associated with chronic inflammatory states, which are linked to immune system dysfunction and/or hyperactivation. The latter might be considered as one of the factors damagin...

Topics

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• Autism Spectrum Disorder Research
• Child Development Disorders, Pervasive
• Child Nutrition and Feeding Issues
• Genetic Variation
• Mutation
• Neuroinflammation and Neurodegeneration Mechanisms
• Prevalence
• Tryptophan and brain disorders

Identifiers and source

Literature Corpus work

c09e5913-9f6d-5b66-8fa8-aad77a51b4ab

DOI

10.21203/rs.3.rs-400114/v1