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Article

Tertiary structure and conformational dynamics of the anti-amyloidogenic chaperone DNAJB6b at atomistic resolution

2023-06-28

Abstract excerpt

<title>Abstract</title> <p>DNAJB6b is a molecular chaperone of the heat shock protein network, shown to play a crucial role in preventing aggregation of several disease-related intrinsically disordered proteins. Despite its importance in maintaining cellular homeostasis, the structure-functional relationship of DNAJB6b is not yet known. Using homology modeling and microsecond-long all-atom molecular dynamics (MD)...

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Literature Corpus work
73ead527-1fb5-589a-8192-de232ce17c14
DOI
10.21203/rs.3.rs-3067238/v1
Open publication

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Tertiary structure and conformational dynamics of the anti-amyloidogenic chaperone DNAJB6b at atomistic resolutionDOI 10.21203/rs.3.rs-3067238/v1
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