Article

Human Placental Genomic Instability Predicts Adverse Pregnancy Outcomes

2025-09-08

Abstract excerpt

<title>Abstract</title> <p>Preeclampsia is a leading cause of pregnancy-related death, accounting for over 50,000 maternal and 500,000 fetal deaths worldwide each year. Preeclampsia has been linked to confined placental mosaicism, which underscores a potential role of placental genomic instability in driving adverse pregnancy outcomes. Here, using bulk RNA sequencing from 59 preeclamptic and 53 normotensive pregn...

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Literature Corpus work: 73d3708e-7c85-5b9f-9fe0-ee594480b823
DOI: 10.21203/rs.3.rs-7419733/v1

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