Article
Timeline metastatic progression: in the wake of the « seed and soil » theory.
Medical oncology (Northwood, London, England) - 6 Oct 2017
Amelot Aymeric, Terrier Louis-Marie, Mazeron Jean-Jacques, Valery Charles-Ambroise, Cornu Philippe, Carpentier Alexandre, Leveque Marc
Abstract excerpt
Little is known about the natural history of cancer and its evolution to metastasis. Paget was the first to postulate the important role played by microenvironment in metastasis progression. Since, the concept of his "seed and soil" theory has been supported and confirmed. Understanding the chronology and natural course that underlie metastasis is mandatory to deepen this concept and to progress in the...
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