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Recent advances in understanding the complexities of metastasis

10 Sept 2018

Abstract excerpt

Tumour metastasis is a dynamic and systemic process. It is no longer seen as a tumour cell-autonomous program but as a multifaceted and complex series of events, which is influenced by the intrinsic cellular mutational burden of cancer cells and the numerous bidirectional interactions between malignant and non-malignant cells and fine-tuned by the various extrinsic cues of the extracellular matrix. In cancer...

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PMID: 30135716
DOI: 10.12688/f1000research.15064.2

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