Article

TOX3 drives hepatocellular carcinoma progression by suppressing the p53-p21-Rb pathway

2026-08-11

Abstract excerpt

<title>Abstract</title> <p> Hepatocellular carcinoma (HCC) has a high recurrence rate and a poor prognosis. Although the transcription factor thymocyte selection-associated high mobility group box factor 3 (TOX3) has diverse roles in cancer, its function in HCC remains unclear. The present study defined TOX3’s mechanistic role and therapeutic potential in HCC progression. TOX3 expression and its correlation with...

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Literature Corpus work: 7332485b-78e5-5a59-9e95-04bdc75b3ccb
DOI: 10.21203/rs.3.rs-9375187/v1

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