Article

Association of lipids in lipoprotein subfractions with liver fibrosis in a mouse model of metabolic dysfunction–associated steatohepatitis

2024-03-26

Abstract excerpt

<title>Abstract</title> <p>Background Metabolic dysfunction–associated steatohepatitis (MASH) exhibits inflammation and fibrosis in addition to lipid accumulation in the liver, which may progress to cirrhosis and liver failure. Liver biopsy is the only method currently available to differentiate between MASH and simple steatosis. Aims This study investigated whether the serum lipoprotein subfraction reflects fi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 72952a15-0400-50eb-9fc1-aca7d75eb5fa
DOI: 10.21203/rs.3.rs-4146700/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Association of lipids in lipoprotein subfractions with liver fibrosis in a mouse model of metabolic dysfunction–associated steatohepatitisDOI 10.21203/rs.3.rs-4146700/v1Read

Phenotypic and Metabolomic Characteristics of Mouse Models of Diet-Induced Hepatic SteatosisSemantic proximity Read

A new dietary rat model fully recapitulates metabolic dysfunction-associated steatotic liver disease pathophysiology and mimics human disease with advanced liver fibrosis and portal hypertensionSemantic proximity Read

Longitudinal analysis of a dietary mouse model of non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH)Semantic proximity Read

Characterization of the metabolic pathways and hepatic macrophage subsets in mouse models of MASHSemantic proximity Read

Human-Mouse Convergence in Metabolic Dysfunction-Associated Steatotic Liver Disease: Mouse Model Selection and Non-Invasive Diagnostic StrategiesSemantic proximity Read

Molecular characterization of liver steatosis through circulating proteins, metabolites and lipidsSemantic proximity Read

Sex- and hepatocyte PPARγ-dependent effects of an obesogenic dietary approach to induce MASH with fibrosis in miceSemantic proximity Read

Hepatic Lipoprotein Production, Cardiometabolic Phenotypes, and Subtypes of Steatotic Liver Disease.Semantic proximity Read

Prevalence of Significant and Advanced Hepatic Fibrosis in Metabolic Dysfunction Associated Fatty Liver Disease (MAFLD)Semantic proximity Read

Sex- and age-associated factors drive the pathophysiology of MASLDSemantic proximity Read

Liver lipid droplet cholesterol content is a key determinant of metabolic dysfunction-associated steatohepatitisSemantic proximity Read

Mediation analysis of the molecular phenotypes in a severe MASH-like liver injury mouse model.Semantic proximity Read